姓名:池晴佳

性别:男

出生年月:1987年03月

职称/职务:副教授/硕士生导师

学位/学历:博士/研究生

硕/博生导师:硕导

联系方式:qingjia@whut.edu.cn

研究方向:水下声场仿真与水下航路规划;机器学习、优化与聚类算法的工程应用

教育背景与工作经历:

2005/09-2009/06 ，ok138cn太阳集团古天乐，学士，工程力学

2009/09-2015/06 ，重庆大学，博士，生物力学工程

2015.7-2017.9 ok138cn太阳集团古天乐ok138cn太阳集团古天乐，讲师

2017.10- ok138cn太阳集团古天乐ok138cn太阳集团古天乐，副教授，硕士生导师

主要教学科研成果:

第一/通讯作者论文

1. Qingjia Chi , Pengchao Liu , Hua-ping Liang*. Biomechanics Assist Measurement, Modeling, Engineering Applications, and Clinical Decision Making in Medicine. Bioengineering. 2022, 22;10(1):20 (JCR Q1, IF 5 )

2. Qingjia Chi, Zichang Yang, and Hua-ping Liang,*A transendothelial leukocyte transmigration model based on computational fluid dynamics and BP neural network, Frontiers in Bioengineering and Biotechnology, 2022, 881797 (JCR Q1, IF 6.064 )

3. Qingjia Chi, Di Wang, and Hua-ping Liang,* A study on drug targets for liver cirrhosis based on unsupervised consensus clustering and immune cell infiltration, Frontiers in Pharmacology, 2022 (JCR Q1, IF 5.988 )

4. Zichang Yang, Quan Zi, Kang Xu, Chunli Wang, Qingjia Chi*, Development of a macrophages-related 4 - gene signature and nomogram for the overall survival prediction of hepatocellular carcinoma based on WGCNA and LASSO algorithm International Immunopharmacology, 2020, 90, 107238 (JCR Q1, IF = 5.714 ，通讯作者)

5. Ji-An You, Yuhan Gong, Yongzhe Wu, Libo Jin, Qingjia Chi*, Da Sun*. WGCNA, LASSO and SVM algorithm revealed RAC1 correlated M0 macrophage and the risk score to predict the survival of hepatocellular carcinoma patients, Frontiers in Genetics, 2022, 730920 (JCR Q1, IF = 4.772 ，通讯作者)

6. Qingjia Chi, Zichang Yang, Kang Xu, Chunli Wang, Huaping Liang*. DNA nanostructure as an efficient drug delivery platform for immunotherapy, 2020, Frontiers in Pharmacology, 10, 1585(JCR Q1, IF= 5.988)

7. Yan Du, Weiguo Wu, Wei Chen, Yongshui Lin* , Qingjia Chi* . Control the structure to optimize the performance of sound absorption of acoustic metamaterial: a review. AIP Advances 2021, 11(6):060701 (JCR Q3, IF 1.697)

8. Qingjia Chi, Xinge Geng, Kang Xu, Chunli Wang, Han Zhao*.Potential targets and molecular mechanism of miR-331-3p in hepatocellular carcinoma identified by weighed co-network network analysis. Bioscience Report, 2020, 40 (6): BSR20200124 (JCR Q3, IF=3.976)

9. Chunming Xu#, Qingjia Chi#, Li Yang, KL Paul Sung*, Chunli Wang*, Effect of Mechanical Injury and IL- 1 β on the Expression of LOXs and MMP- 1, 2, 3 in PCL Fibroblasts after co-culture with Synoviocytes Gene 2020, 766, 145149 ( JCR Q2, IF = 3.913 ，共同一作)

10. Rui Xu, Qibiao Wu, Yuhan Gong, Yongzhe Wu, Qingjia Chi*, , Da Sun, *A novel prognostic target- gene signature and nomogram based on an integrated bioinformatics analysis in hepatocellular carcinoma. Biocell 2021 (IF = 1.254)

11. Chunli Wang #, Qingjia Chi#, Yongqiang Sha, Kang Xu, Chunming Xu, Cheng Chen , Wei Huang , Peixing Chen, Peter Chen, Li Yang* , KL Paul Sung *Effect of mechanical injury and IL- 1 β on LOXs and MMP- 1, 2, 3 expression in ACL fibroblasts co-cultured with synoviocytes. Biotechnology Letter, 2020, 42, 1567– 1579 (SCI, JCR Q3, IF=2. 154 ，共同一作)

12. Han Zhao, Kang Xu, Peng Zhu, Chunli Wang, Qingjia Chi*. Smart hydrogels with high tunability of stiffness as a biomimetic cell carrier. Cell Biology International, 2019. 43(2): 84-97. (SCI, JCR Q3, IF=2.571)

13. Qingjia Chi, Zhen Wang, Feifei Tian, Ji’an You, Shuang Xu*. A review of fast bubble- driven micromotors powered by biocompatible fuel: Low- concentration fuel, bioactive fluid and enzyme. Micromachines, 2018. 9( 10): 537. (SCI, JCR Q3, IF=2.426)

14. Qingjia Chi, Jieling Shan, Xiaorong Ding, Tieying Yin, Yazhou Wang, Dongyu Jia, Guixue Wang* . Smart mechanosensing machineries enable migration of vascular smooth muscle cells in atherosclerosis-relevant 3D matrices 2017 Cell Biology International 41 (6), 586-598 .(SCI, JCR Q3, IF = 2. 127)

15. Jieling Shan#, Qingjia Chi#, Hongbing Wang, Qiping Huang, Li Yang, Guanglei Yu and Xiaobing Zou* , Mechanosensing of cells in 3 D gel matrices based on natural and synthetic materials. Cell Biology International 2014, 38( 11), 1233- 1243(JCR Q2, IF = 2. 127 ，共同一作)

16. Qingjia Chi, Tieying Yin, Hans Gregersen, Xiaoyan Deng, Yubo Fan, Jingbo Zhao, Donghua Liao, Guixue Wang* , Rear actomyosin contractility driven directional cell migration in three-dimensional matrices: a mechano-chemical coupling mechanism. Journal of the Royal Society Interface 2014, 11,20131072 (JCR Q1, IF = 3.856)

17. Qingjia Chi, Guixue Wang, Jiahuan Jiang*, The persistence length and length per base of single-stranded DNA obtained from fluorescence correlation spectroscopy measurements using mean field theory. Physica A 2013, 392(5): 1072- 1079 (JCR Q2, IF = 1.373)

18 . Qingjia Chi, Jiahuan Jiang* , A bead-spring model and mean field theory based re- calculation reveals uncertainty of Rouse-type DNA dynamics in dilute solution. Biomedical Engineering- Applications Basis Communications 2 0 1 2 , 2 4 ( 4 ): 355-364 (JCR Q4, IF = 0.236)

主要科研项目:

1. 张力作用下DNA的柔化行为研究，主持，国家自然科学基金青年项目，2017.01-2019.12，22万元

2. 水下声源激发的海水表面波理论模型与特性分析，主持，海军工程大学外协项目，10.56 万元，2022.6-2022.10

3. 军队生物安全研究专项——急性感染时宿主应答的多组学关键分子靶标鉴定及候选药物筛选，子课题负责人，80 万元，2021.12-2023.6 (省部级纵向)

4. 模拟声纳布放舱方舱研制，主持，军工横向，中国船舶重工集团第七一〇研究所外协项目，60.5万元，2019.9-2020.8

5. 航路规划模块研制，主持，军工横向，19.5万元，2023.7-2023.12

6. 声场定位仿真模型，主持，军工横向，4.9万元，2023.11-2024.6

7. 肿瘤微环境生物的生物信息学与研究，主持，横向项目，25 万元， 2022.2-2025.2

8. 细胞迁移过程中DNA 断裂的生物力学机理研究，主持，重庆大学生物流变科学与技术教育部重点实验室开放基金，5万元，2018.6-2020.6

学术兼职:

Biocell副主编

Hepatoma Research青年编委